Pappenheimer bodies

They are mostly observed in diseases such as myelodysplastic syndrome (MDS), sideroblastic anemia, hemolytic anemia, lead poisoning and sickle cell disease.

They can interfere with platelet counts when the analysis is performed by electro-optical counters.

[4] Pappenheimer bodies are visible with a Wright and/or Giemsa stain.

Confirmation of non-heme iron in the granules is made with a Perls' Prussian blue stain, and this atypical red blood cell is then known as a siderocyte.

ASH Image Bank (2004); doi:10.1182/ashimagebank-2004-101168 (Retrieved from https://web.archive.org/web/20090106200424/http://ashimagebank.hematologylibrary.org/cgi/content/full/2004/0722/101168 on January 17, 2011.