Para powerlifting was one of the sports contested at the 2022 Commonwealth Games, held in Birmingham, England.

This was the sixth staging of para powerlifting at the Commonwealth Games since its inclusion in 2002, and the second staging within England specifically.

The competition took place on 4 August 2022, spread across four weight classes (two per gender).

[3] Five other sports - badminton, boxing, netball, table tennis, and weightlifting - also took place there.

[4] A total of 40 powerlifters (20 per gender) qualified to compete at the Games.