[3][5][6] Paraflabellina ischitana usually can be found in shallow water, but it can also reach depths of 35 m.[3] This species can grow to a length of approximately 4 cm and is mostly purple-violet in colour.

It has opaque white-tipped certa, rhinophores, and oral tentacles.

[7] Due to the somewhat transparent skin of the ceras, the branches of the digestive gland are visible, and appear as red-orange.

[3][5][6][8][9][10] Paraflabellina ischitana is often confused with Flabellina affinis, but can be distinguished as follows:[3][6] Paraflabellina ischitana is also similar to Edmundsella pedata, but they can be distinguished on the basis of their rhinophores:[7] This nudibranch likely eats hydroids of the genus Eudendrium (Eudendrium racemosum and Eudendrium glomeratum) as its main food source.

The nudibranch places the egg case on the branches of hydrozoa.