When this group of rowdy and raunchy, laid-back medics are transferred from their cushy uptown district to the rough south-end, they find plenty of trouble when they discover the tough guys are playing a "corpses-for-dollars" scam and they want to crack the case.

All of this Uptown is dealing with his girlfriend, Savannah, who wants him to focus and go to med school, and Mad Mike, who is smitten with a French woman (Liette), who is transporting a heart from France that is needed for a transplant.

There is a subplot about a mystery woman named "Danger Girl" who seduces her lovers to the point they meet with bizarre accidents, as was the case of the judge who had a near fatal heart attack and a man who drove his car into a water fountain.

At the end of the film, she meets up with Captain Prescott, who much to his chagrin, has been named Deputy Chief of the South District, on the recommendation of heroes Uptown and Mad Mike, who receive special recognition for breaking up the black market scheme.

Lions Gate Home Entertainment has not announced any current plans to release the film onto DVD.