The female reproductive system is composed of two embryological segments: the urogenital sinus and the paramesonephric ducts.

During this time, primordial germ cells migrate from the yolk sac to the genital ridge; a region of mesenchyme arising from, and running parallel with, the mesonephros.

The paramesonephric ducts are formed by the craniocaudal invagination of a ribbon of thickened coelomic epithelium that extends from the third thoracic segment caudally to the posterior wall of the urogenital sinus.

In contrast, the paramesonephric ducts begin to proliferate and differentiate in a cranial-caudal progression to form the aforementioned structures.

The genes expressed play a critical role in mediating the regional characterization of structures found along the cranial-caudal axis of the female reproductive tract.

However whenever an individual exhibits persistent Müllerian duct syndrome, the ductus deferens will run along the lateral sides of the uterus.

Many types of disorders can occur when this system is disrupted ranging from uterine and vaginal agenesis to the duplication of unwanted cells of the uterus and vagina.

[9] Due to improved surgical instruments and technique, women with paramesonephric duct anomalies can have normal sexual relations.

Assisted reproductive technology makes it possible for some women who have paramesonephric duct anomalies to conceive and give birth to healthy babies.