[2] Seeds in the genus generally require at least two years to germinate, producing seedlings described by American botanist and gardener Robert Nold as "incredibly small and look exactly like columbines dancing on the head of a pin".
[4]: 50 The species was first described as Isopyrum uniflorum by British botanists James Edward Tierney Aitchison and William Hemsley in 1882.
[1] In a 1920 article for the Royal Botanic Gardens, Kew's Bulletin of Miscellaneous Information, the British botanists James Ramsay Drummond and John Hutchinson segragatated the genus Paraquilegia from Isopyrum and renamed the species Paraquilegia uniflora.
[7] Paraquilegia uniflora is native to a range spanning Tajikistan to the mountainous border between Afghanistan and northern Pakistan.
[2][1] As of 2025[update], the Royal Botanic Gardens, Kew's Plants of the World Online, utilizing the Angiosperm Extinction Risk Predictions v1, predicts that Paraquilegia uniflora is a "not threatened" species with a confidence level of "low confidence".