The Parkesburg National Bank is an historic, American bank building that is located in Parkesburg, Chester County, Pennsylvania.

[1] This historic structure was built in two sections; the older dates to 1883 and the second to circa 1900.

Both are three-story, brick structures that sit on banked basements.

The older section has a patterned slate mansard roof with rounded dormer windows and was designed in the Second Empire style.

The addition is faced in concrete, with floral patterns, a lion's head, and the bank's insignia.