A station building exists at the stop, but is not currently used as a ticket office.

Parkesburg has two low-level side platforms; a center track is not used for passenger service.

From c. 1914 until 1972, Parkesburg Tower was located near the Atlantic Avenue bridge.

The tower served as a communication/signalling point for westbound (to Lancaster and beyond) trains, and a routing location for eastbound trains entering the Main Line of the Pennsylvania Railroad.

It was truncated to Downingtown November 10, 1996[4] because of the need for trains to deadhead to Lancaster to turn around.