Partridge-Sheldon House is a historic home located at Jamestown in Chautauqua County, New York.

It is a three-story Second Empire style residence built between about 1850 and 1867, and substantially renovated and enlarged about 1880.

The structure features a Mansard roof with patterned and polychromed slate, decorative eave brackets, and an imposing Mansard-roofed front porch with ornamental iron cresting.

[2] The house is owned and maintained by the Jamestown Chapter of the Daughters of the American Revolution.

This article about a historic property or district in Chautauqua County, New York, that is listed on the National Register of Historic Places, is a stub.