Piacenza beat Cagliari in a relegation playoff, which was a successful end for Luiso at the club since he was bought by Coppa Italia winners Vicenza.

He did, however, help the team to the semi-finals of the UEFA Cup Winners' Cup during his first season with the club,[1] finishing the competition as the top scorer,[2] also later helping Vicenza to re-obtain Serie A promotion by winning the 1999–2000 Serie B title.

[3] Following the second relegation, Sampdoria signed Luiso, who scored 13 goals in 47 Serie B fixtures for the club.

Following a mere three Serie A fixtures in Ancona's disastrous season, before a short spell at Catanzaro in 2004, Luiso's professional career ended.

Luiso served as the head coach of Sora in the Italian Eccellenza division from 2010 to December 2011.