The Passavant House is an historic, American home that is located in Zelienople, Butler County, Pennsylvania.

The interior features a large collection of furniture, clothing, personal and household items, particularly of the Passavant family, dating back to the early 1800s.

William Passavant (1821–1894), who was born in the house and became known for his charitable works on behalf of the Lutheran community in the United States.

The simple 2+1⁄2-story, three-bay by two-bay, brick dwelling sits on a sandstone foundation.

Built in 1809, a two-story frame addition was added to the rear circa 1820.