Pathans of Sind or Sindhi Pathan (Sindhi: پٺاڻ) are communities of Pashtun descent settled in Sindh and can be referring to Sindhified Pashtun communities.

The vast majority of Sindhi Pathans originate from Quetta and southern Afghanistan, and a few come from Khyber Pakhtunkhwa.

Shikarpur, New Zarkhail, Pir Bux Khan Wandh, Garhi Yasin, and Sultan Kot Shahpur Chakar, whereas others live in other urban, sub-urban, and rural areas of Sindh.

The tribes most commonly found in the Sindh region are the Tareen, Muhammadzai, Niazi, Kundi, Miana, Bangash, Yusufzai, Hassan Zai, Mandanr, Lodi, Kakar, Shinwari, Sherwani Orakzai, Sulemankhel Sulemani, Afridi, Khattak, Kakazai, Karlani, Barakzai, Khizerzai, Babar, and the Zamand Pathans.

Also, it's estimated that 30% of the Urdu-speaking Muhajirs of Karachi and Hyderabad make a claim to the ancestry of Pashtuns that mostly assimilated into North Indian culture.