[3] Patient Number 9 received favourable reviews from music critics and won Best Rock Album at the 65th Annual Grammy Awards.

[1][6] On 24 June 2022, the lead single and title track, "Patient Number 9" featuring Jeff Beck, was released along with an accompanying music video.

[15][16] Osbourne performed during the halftime show at the Los Angeles Rams' NFL season opener against the Buffalo Bills on 8 September in support of the album.

He wrote: "Even with that fatalistic perspective sometimes peeking through, Ozzy sounds hypercharged throughout Patient Number 9, continuing the unlikely late-in-the-game comeback he began on Ordinary Man, and besting that album by taking more chances.

"[19] Furthermore, writing for The Guardian, Alexis Petridis gave the album an overall positive review, implying that "By way of contrast, Patient Number 9 draws to a close with God Only Knows, a beautiful stadium rock ballad that features Osbourne contemplating his own mortality in terms that are alternately starkly affecting.

"[22] Metal Hammer gave the album a positive review and stated: "Despite everything you may have heard about Ozzy being on his last legs, Patient Number 9 unequivocally does not sound like the work of a man living on borrowed time.

Instead, it sounds like the Prince of fucking Darkness having an absolutely smashing time, with a bunch of his mates and, weirdly, a newfound sense of artistic ambition.

"[23] NME writer Rhian Daly gave Patient Number 9 almost perfect score and stated: "At 73 years old and battling with his health, you might not expect Osbourne to keep that bar particularly high.