Patrizio Marco Giovanni "Patrick" Mameli (born 23 November 1966) is a Dutch musician who is the founder, lead singer, guitarist and only original remaining member of the technical death metal band Pestilence, which he formed in 1986.

[1] Mameli remains the creative force behind Pestilence, as well as the primary songwriter.

During Pestilence's break up, Mameli resurfaced in the Dutch groove metal supergroup C-187 with Cynic drummer Sean Reinert and bassist Tony Choy (formerly in Pestilence), resulting in 2007's Collision.

In 2018, Mameli toured again with Pestilence with no original members, joined by Slovenian bassist Tilen Hudrap who famously played with genre-defining, iconic bands U.D.O, Testament, Doro, Vicious Rumors, Paradox and many more.

Mameli found in his own words “the best drummer ever in Pestilence”, Septimiu Harsan, known for his versatility and technical abilities.