She was Serie A's top scorer on 14 occasions (an Italian record for her category) and spent part of 2010 in the United States, representing Women's Professional Soccer (WPS) club Sky Blue.
[3] In addition to Torres, Panico played for Lazio, Torino, Modena Amadio, Milan and Bardolino, as well as Sky Blue of the United States' Women's Professional Soccer (WPS).
[5] In the months before the professional Women's United Soccer Association (WUSA) began play in 2001, Panico was pursued by Philadelphia Charge.
[6] Panico made her senior international debut on 8 April 1996, in Italy's 4–1 UEFA Women's Euro 1997 qualifying win over Portugal in Mestre.
At the 1999 FIFA Women's World Cup in the United States, Panico gave Italy the lead in their first game against Germany.
[15] On 2 October 2010, she scored against Ukraine for the FIFA Women's World Cup qualification at the Stadion Yuri Gagarin in Chernihiv.