PT-143 was a PT-103-class motor torpedo boat of the United States Navy that served during World War II.

PT-143 was ordered by the United States Navy and laid down on 13 July 1942 at the Elco Works of the Electric Launch Company (now Electric Boat Company) at their Bayonne, New Jersey shipyard; launched on 25 September 1942; and completed on 13 October 1942.

[3] In the early morning of 4 March 1943, during the Battle of Bismarck Sea, 10 PT boats under Atkins were sent to attack the surviving convoy off Lae.

[4] PT-119 and PT-132 hit flotsam and had to return to base while PT-143 (under Lieutenant Junior Grade John S. Baylis USNR) with PT-66, PT-67, PT-68, PT-121, PT-128 (MTBRon 7), PT-149, and PT-150 continued on.

[5] On 28 October 1945 at Samar, Philippines, PT-143 was decommissioned, stripped of usable items, and destroyed by U.S. military personnel.