Having suffered a decline in popularity in the following decade,[2] she experienced a career revival in mid-late 1990s and reinstated her position on Italian music charts.

Her most popular songs include "La bambola" (1968), "Pazza idea" (1973), "Pensiero stupendo" (1978), and "...E dimmi che non vuoi morire" (1997).

[4][5] She spent her formative years in Venice where she was acquainted with American poet Ezra Pound and the future Pope John XXIII.

[2][4] She started taking piano, dance and solfège classes from a young age, and entered the Benedetto Marcello Music Conservatory straight into the fourth grade when she was ten.

[4][6][9] Having secured a contract with RCA Italiana, Patty released her first single in late 1966, "Ragazzo triste" (English: "Sad Boy"), the Italian version of "But You're Mine" by Sonny & Cher.

Pravo scored another top 20 single in 1967, "Se perdo te" ("If I Lose You"), written by English songwriter Paul Korda and originally performed by P. P. Arnold as "The Time Has Come".

She made brief appearances in various Italian films, including Camillo Mastrocinque's The Most Beautiful Couple in the World and two pictures by Mariano Laurenti, usually performing the popular song "Qui e là" ("Here and There").

In autumn 1969, she released another top 20 single "Nel giardino dell'amore" ("In the Garden of Love") which she performed to some success in the variety show Canzonissima.

Pravo took part in the Sanremo Music Festival 1970 with the song "La spada nel cuore" ("A Sword in the Heart") performed in duet with Little Tony.

The LP reached the top 10 of the Italian chart and included the hit "Per te" ("For You"), and a duet with Robert Charlebois "La solitudine" ("Loneliness").

Pravo found success in France, where she was dubbed "Italian Édith Piaf" for her interpretation of "Non, je ne regrette rien".

Although it was her lowest-charting album at that point, it spawned the popular Italian version of Jacques Brel's "Ne me quitte pas", titled "Non andare via", and another top 5 hit "Tutt'al più".

The following two LPs, Per aver visto un uomo piangere e soffrire Dio si trasformò in musica e poesia (To See a Man Cry and Suffer, God Turned Himself into Music and Poetry) and Sì... incoerenza (Yes... Inconsistency), did not fare as well, but still placed within the top 20.

The album was highly experimental in nature, introducing rock and funk into Pravo's music, and heavily using uncommon at that time synthesizers.

Some of the songs from this LP were performed in the controversial Italian TV show Stryx, in which Pravo appeared alongside such singers as Amanda Lear and Grace Jones.

However, the song's parent album, Occulte persuasioni (Hidden Persuasions), released by CGD, failed to make an impact on the sales chart, despite favourable reviews.

Her song "Pigramente signora" ("Lazily a Lady") was a cover of Dan Fogelberg's "To the Morning", yet the singer was accused of plagiarism.

Pravo released an album titled Pazza idea with new versions of her old material, and in 1988, the LP Pigramente signora, a collection of songs she had recorded in the past few years, including the recent single "Contatto".

In 1990, Pravo was due to perform the song "Donna con te" ("Woman with You") at Sanremo, but shortly before the event, she raised reservations towards the lyrics and asked for major changes.

[36] In 1995, Pravo returned to the Sanremo Festival with the song "I giorni dell'armonia" ("Days of Harmony"), but it was met with lukewarm reception.

This time it was a triumph and the ballad "...E dimmi che non vuoi morire" ("...And Tell Me You Don't Want to Die") won the Mia Martini critics' award in addition to placing 8th in the voting contest.

On her next studio album, Notti, guai e libertà (Nights, Trouble and Freedom), Pravo worked with some renowned Italian songwriters, including Ivano Fossati, Franco Battiato and Lucio Dalla.

It was a collaboration with young, largely unknown songwriters and presented an innovative, avant garde sound, with most songs co-written by Pravo herself.

In September 2007, she released the album Spero che ti piaccia... Pour toi (I Hope You Like It... For You) through a small label Kyrone Music.

It promoted her next studio album, Nella terra dei pinguini (In the Land of Penguins), released in February 2011 by Carosello Records.

In early 2012, Patty released the single "Com'è bello far l'amore" ("How Nice It Is to Make Love") from Fausto Brizzi's film of the same name, and the song went on to win the "Italian Golden Globe".

She made a cameo appearance as herself in the 2014 Greek film Xenia, directed by Panos H. Koutras, which tells about two brothers who are obsessed with her music.

[46] In February 2016, Pravo performed the song "Cieli immensi" ("Immense Skies") at the Sanremo Festival, placing 6th and winning her third critics' award.

[47] Musically, it veered towards more commercial pop and included collaborations with such artists as Emis Killa, Fred De Palma and Baustelle.

In early 2020, Pravo appeared as a judge on Il cantante mascherato, Italian edition of the TV show Masked Singer.