Adelstein co-created the dark comedy TV series Imposters, which aired on Bravo and ran for two 10-episode seasons from 2017 and 2018; he is credited as a writer on 6 episodes.

[1] Prior to his professional acting career, Adelstein attended the progressive Francis W. Parker School, then Bowdoin College where he graduated Phi Beta Kappa and summa cum laude with a degree in English.

In 2005, he received his most significant role to date as a member of the regular cast of the suspenseful television series Prison Break.

He played the main role of Jake Novak, the husband of Abby McCarthy (Lisa Edelstein) in Girlfriends' Guide to Divorce, which premiered in late 2014 as the first scripted original series for Bravo.

[3] In April 2016, he was cast as Raymond Blackstone in the Hulu series Chance, starring Hugh Laurie.

[12][13] Weil filed for divorce from Adelstein in March 2016,[14] requesting joint custody of their daughter.