Throughout its run, the show relied heavily on Gilmartin's improvisational abilities and the easy-going rapport he established with his string of female co-hosts.

One critic dubbed it, "the first television show to combine well-worn theatrical movies, improvisational comedy and culinary education.

The long-format interview style show examines lives affected by mental health issues, including depression, addiction, fear, anxiety, abuse, and gender identity.

Club as "a patient and empathetic interviewer", and The New York Times noted that with these hosting abilities, he had created "a perversely safe place in which he and his guests talk about their fears, addictions and traumatic childhoods.

Notable guests include Tiffany Haddish, Theo Fleury, Maria Bamford, Aisha Tyler, Dan Harris, Paul F. Tompkins and Doug Benson.

Following a major depressive episode in 2003, in which Gilmartin experienced suicidal thoughts, he entered treatment and discovered he had drug and alcohol addiction.