Paul Reinman was born in Germany[4] and raised in Pfiffligheim, a borough of Worms, seat of one of the oldest Ashkenazi Jewish communities.

The second of five children, and the eldest son, of real-estate agent and farm-produce broker Bernhard and his wife, he began drawing at age 3.

By his early twenties, he was creating pen-and-ink drawings of such subjects as the Rashi Synagogue, which was shortly afterward destroyed by the Nazis.

[3] In the 1930s, Reinman entered the field of commercial art in New York, recalling in 1988, My first job was as assistant to a designer of neon signs.

His earliest known signed story is the 12-page "Plague of the Poisoned Jewelry", starring super-speedster the Whizzer, in Timely's All Winners Comics #2 (Fall 1941).

He then draws comparisons to Nazi atrocities perpetrated by the Third Reich.... Paul Reinman renders this broadcast in newsreel fashion starting off with a magnificent full-page splash depicting a score of inhumanly bound and slaughtered U.S. Marines.

After the advent of the company's first superheroes and its evolution into Marvel, Reinman would ink Kirby on numerous landmark books, including The Incredible Hulk #1 (May 1962), The X-Men #1-5 (Sept. 1963 – May 1964), and The Avengers #2, 3 & 5 (Nov. 1963, Jan. & May 1964).

[6] In 1965, Reinman left Marvel and with Superman co-creator Jerry Siegel created The Mighty Crusaders for Archie Comics' short-lived superhero line.

The prolific Reinman's other work includes numerous issues of Adventures into the Unknown and Forbidden Worlds for the small American Comics Group (AGC) in the 1950s and 1960s.

He and writer-editor Richard E. Hughes co-created the spy character John Force in ACG's Magic Agent #1 (Feb.