Prior to her election to Parliament, Sherriff worked in the police force, providing victim support, and in community care on the NHS frontline.

[8] In September 2015, she secured an agreement from WHSmith to reduce the price of their goods in hospitals, against whom had she had launched a campaign for exploiting vulnerable patients and their families.

[10] Sherriff became the first backbench MP in Parliamentary history to have an amendment to a government Budget resolution successfully adopted when her motion to abolish the "Tampon Tax" was passed.

[22] In 2020, Sherriff twice unsuccessfully stood for a seat on the Labour Party's National Executive Committee in a spring by-election and an autumn regular election.

[23] She stood as an independent in the by-election, but was endorsed by the Tribune group of MPs in the subsequent contest alongside former MP Liz McInnes and former MEP Theresa Griffin.

[24][25] In 2020, Sherriff announced her candidacy to contend the Labour nomination for the new office of Mayor of West Yorkshire, however, she withdrew due to her breast cancer treatment.