The first freeway interchange is at East 40th Avenue, which also provides traffic access to and from to Aurora's Airport Boulevard running to the south.

An interchange with Green Valley Ranch Boulevard provides access to the neighborhood of the same name.

The East 56th Avenue interchange is the final exit along Peña Boulevard before it turns east near the Rocky Mountain Arsenal National Wildlife Refuge, and reaches the interchange with Tower Road, which serves several airport hotels.

Once inside airport grounds, the freeway intersects the car rental return area, and connects to the parking garages and terminal access roads.

[7] Ten thousand people were employed during the construction of the airport and the connecting freeway.