He was born in Cork in 1923, son of John Wyse (or Wise), pawnbroker's clerk, and his wife Julia (née Cronin), a native of Macroom.
[2] Five years later he was first elected to Dáil Éireann as a Fianna Fáil Teachta Dála (TD) and running mate of Jack Lynch at the 1965 general election for the Cork Borough constituency.
[4] Wyse supported George Colley in the 1979 Fianna Fáil leadership election which was won by Charles Haughey, and he was dropped from the junior ministerial ranks.
Wyse opposed Haughey in every leadership challenge from when he assumed the role, becoming a member of the so-called Gang of 22.
He remained a member of Cork City Council until he retired in 1999, having held his seat for almost forty years.