Calomino spent nearly all of his career in Boca Juniors, having also played 37 games for the Argentina national team where he scored 5 goals.

[6] With Argentina he won the 1921 South American Championship, the first official title for the national team.

His good performances led him to be promoted to upper divisions, debuting in the senior squad in 1911,[6] when Boca still played in Segunda División.

In 1912 he moved to Argentino de Quilmes, where he was soon regarded as the best right winger in Argentina.

Calomino had brief returns to Boca Juniors (1913) and Argentino de Quilmes (1914), also playing for Hispano Argentino until 1915 when he returned to Boca Juniors, playing there until the end of his career in 1924.