[2]Peg Entwistle reportedly migrated from Britain to America, sailing from Liverpool aboard the S.S. Philadelphia in 1916, and settled in New York City.

Walter Hampden gave Entwistle an uncredited walk-on part in his Broadway production of Hamlet, which starred Ethel Barrymore.

[10] Entwistle performed in ten Broadway plays as a member of the Theatre Guild between 1926 and 1932, working with noted actors such as George M. Cohan, William Gillette, Robert Cummings, Dorothy Gish, Hugh Sinclair, Henry Travers and Laurette Taylor.

Changing characters every week, Entwistle garnered some publicity, such as an article in the Sunday edition of The New York Times in 1927[8] and another in the Oakland Tribune two years later.

[13] Aside from a part in the suspense drama Sherlock Holmes and the Strange Case of Miss Faulkner and her desire to play more challenging roles, Entwistle was often cast as a comedian, most often the attractive, good-hearted ingénue.

[13]In early 1932, Entwistle made her last Broadway appearance, in J. M. Barrie's Alice Sit-by-the-Fire,[14] which also starred Laurette Taylor, whose alcoholism led her to two missed evening performances and refunds to ticket-holders.

Florence "Flo" Lawrence, theatre critic for the Los Angeles Examiner, gave the production a very favorable review: Belasco and Curran have staged the new play most effectively and have endowed this Romney Brent opus with every distinction of cast and direction.

In the cast Peg Entwistle and Humphrey Bogart hold first place in supporting the star (Billie Burke) and both give fine, serious performances.

Thirteen Women stars Myrna Loy and Irene Dunne in a pre-Hays code, high-budget thriller produced by David O. Selznick and drawn from the novel by Tiffany Thayer.

[20] It premiered on 14 October 1932, a month after her death, at the Roxy Theatre in New York City, and was released in Los Angeles on 11 November to neither critical nor commercial success.

The police surmised that instead she made her way to the nearby southern slope of Mount Lee to the foot of the Hollywoodland sign, climbed a workman's ladder to the top of the "H" and jumped.

[30] In 2014, roughly 100 people marked the anniversary of Entwistle's death by gathering in the parking lot of Beachwood Market in Hollywood, to watch Thirteen Women on an outdoor screen.

Proceeds from a raffle and from food and beverages sold at the screening were donated to the American Foundation for Suicide Prevention in Entwistle's name.

Jakko Jakszyk's song "Damn This Town" (from his 1995 album Mustard Gas and Roses) mentions Entwistle and her suicide.

The song imagines Peg Entwistle standing atop "The big white letter H" as she wonders whether she will be remembered after her death.

"[36] Ryan Murphy's 2020 miniseries Hollywood revolves around the fictional production of a film, Peg, about Entwistle's acting career and suicide.

The lyrics heavily feature alliteration on the letter "H" and contain several references to Entwistle's death, including the height of the Hollywood sign and the discovery of her remains by a hiker.