He moved to Major League Soccer in March 2004 to play for Colorado Rapids.
In his second season, he scored seven goals and had six assists before the Rapids traded Peguero to New York Red Bulls in April 2006 for Thiago Martins The deal also included the Red Bulls sending to the Rapids first-round and third-round picks in the 2007 MLS SuperDraft.
[7] After over two years out of the game, Peguero resumed his career when he signed with Fort Lauderdale Strikers of the North American Soccer League in April 2011.
He made his full debut for the Haitian national team in a July 2003 friendly match against St Kitts & Nevis.
In March 2009, Peguero made a comeback for the national team, playing the last 16 minutes of a 4–0 friendly match loss to Panama.