Soon after settling, Peiró established lime kilns for producing quicklime and storage warehouses for grain from the surrounding region, which was still referred to as "Paineiras" at the time.

The station continued to operate until 1970, when the depletion of limestone and a fatal railway accident near the village that year led to disruptions in train services, resulting in its closure in 1971.

This find drew interest from the National Department of Mineral Production (DNPM), leading paleontologist Llewellyn Ivor Price to visit the site for further study.

During the 1980s, supporters of scientific causes and local residents initiated a non-governmental project aimed at preserving Peirópolis as a dedicated research site for its geological and paleontological heritage.

[8][9] Discoveries in the area include titanosaurs Uberabatitan ribeiroi, Trigonosaurus pricei and Baurutitan britoi, crocodyliforms Uberabasuchus terrificus, Peirosaurus tormini, and Itasuchus jesuinoi, podocnemids Peiropemys mezzalirai and Pricemys caiera, the ground sloth Eremotherium laurillardi, and the anura Uberabatrachus carvalhoi.