[5][7] In the early years of its existence, Pennsylvania Hall contained the students' living quarters, as well as several offices and recitation rooms.

On July 1, Michael Jacobs, the chemistry and mathematics professor at the college led Union officers to the cupola to observe the battlefield.

[6]: 5–7 Soldiers of both armies were treated in Pennsylvania Hall, as control of the College shifted from Union to Confederate forces on the evening of July 1.

)[11] A structural renovation of Pennsylvania Hall began January, 1969, to maintain the stability of the exterior walls, roof, and cupola with steel columns, girders and 5 concrete reinforced slabs (1 for each floor, including the attic).

The offices of the college's president and provost are located in the building, as well as the human resources and financial services departments.