Past this interchange, the road heads through wooded areas within the John Heinz National Wildlife Refuge at Tinicum before crossing the Darby Creek into the borough of Prospect Park.

Here, PA 420 curves north and becomes four-lane undivided Lincoln Avenue, heading into residential areas.

The road narrows to two lanes and passes more homes and businesses, running through the downtown of Prospect Park.

The route crosses under CSX's Philadelphia Subdivision railroad line, at which point it enters Ridley Township and becomes Kedron Avenue.

PA 420 continues through suburban development, curving to the northwest and passing near more residential neighborhoods.

Past this, the road heads through commercial development with some homes to the northeast, continuing into Springfield Township.

The road gains a center left-turn lane and passes businesses as it comes to a grade crossing with SEPTA's light rail Media–Sharon Hill Line west of the Woodland Avenue station.