The site of Therry and Geoghegan Colleges now is the home to the Penola's Senior Campus (Years 9–12) which is located on Gibson Street, Broadmeadows.

The Junior Campus of Penola (Year 7–8) is located on the original site of Sancta Sophia College in Glenroy.

The trunk of the tree is represented by the cross and points to the life of Christ as a model for the members of Penola Catholic College.

The three words surrounding the emblem of Penola Catholic College are Faith, Excellence and Community which are the cornerstones of our school.

Penola, a small town in the south-east of South Australia, is where Mary MacKillop opened her first school in 1866 and where together with Julian Tenison Woods she founded the order of the Sisters of St Joseph of the Sacred Heart.