Peoria High School was originally located in the back of a general store/post office combination and taught by a single teacher in 1919, but after a railroad was built in the city, a new building opened in 1922, enrolling 50 students.

[2][3] At its opening, the school, built in the Spanish Colonial Revival style, was the largest structure in town and contained period luxuries such as indoor plumbing.

[7] Peoria High School offers various academic tracks: basic, honors, and Advanced Placement (AP).

The honors program offers a somewhat harder work load, countered by a weighting the grade point average differently.

[9] The graduation ceremony takes place at the State Farm Stadium, which is located in the neighboring city of Glendale.