Two-Mix Perfect Best (TWO-MIX パーフェクト・ベスト, Tū Mikkusu Pāfekuto Besuto) is the fifth compilation album by J-pop duo Two-Mix, released by King Records on June 8, 2011.

The album covers the duo's singles, B-sides, and other tracks from 1995 to 1998.

It was the duo's first new release since the 2002 box set Two-Mix Collection Box: Categorhythm.

103 on Oricon's weekly albums chart.

[3] All lyrics are written by Shiina Nagano; all music is composed by Minami Takayama, except where indicated; all music is arranged by Two-Mix.