In the final at the Stade de France, he finished in 48.24 seconds after Félix Sánchez and Joey Woody.

Iakovakis achieved his personal best of 47.82 seconds on 6 May 2006 in Osaka during the IAAF World Athletics Tour and won his first major competition 3 months later.

He won the bronze medal at the 2009 IAAF World Athletics Final, which was the last edition of the competition and was held in Thessaloniki.

He suffered a minor injury to his soleus muscle in March, but recovered and began his preparation in South Africa and Cyprus.

He marked a resurgence in form at the 2012 Greek Championships by winning his 15th straight national title, including a run of 49.04 seconds in the heats.