Pernis (Dutch pronunciation: [pɛrˈnɪs])[1] is a neighborhood and submunicipality (since 3 March 2010) of Rotterdam, Netherlands.

The district has a population of 4,845 (2018) on a total area size of 1.60 km2 (0.62 sq mi).

Pernis is thus a full submunicipality of Rotterdam, but the former independent municipality had its own district council already.

Although surrounded by ports, Pernis has preserved its village-like atmosphere very well.

It remained an independent municipality until 1934, when it was merged into Rotterdam.