Antić has played with: Rabotnički Skopje, AEK Athens, Crvena zvezda, Academic Sofia, Lokomotiv Kuban, Spartak St. Petersburg and Olympiacos.

[8] After a series of solid performances as a starter for the Hawks, Antić was selected as a participant in the Rising Stars Challenge game for the NBA All-Star 2014 in New Orleans.

[9] However, because of an injury to his right ankle, Antić was forced to miss the All-Star weekend, being replaced by the Phoenix Suns' big man Miles Plumlee.

Antić was a starter in the first game of the series, tallying 8 points and 7 rebounds in his playoff debut while also successfully guarding All-Star center Roy Hibbert.

While hardly the revelation of the tournament, he fulfilled his full potential at the EuroBasket, and was the cornerstone of the Macedonian national team's defensive strategy, that propelled them to the top four.

He is adept at pick and roll play, which coupled with his excellent three-point shooting accuracy for a player of his position, makes him a scoring threat from all distances.

Antić demonstrated particular determination and confidence when guarding opposition star players, such as Dirk Nowitzki and Pau Gasol at the EuroBasket 2011.

[22] Antić has several tattoos, including ones of his family,[23] Crvena zvezda team supporters (Delije) badge on his right under-arm,[19][24] and a stylized flag of Macedonia on his right chest.

[26] After the FIBA EuroBasket 2011 in Lithuania, Antić was awarded with the Honoris causa academic title, by FON University in Skopje.

[27] On April 8, 2015, Antić and teammate Thabo Sefolosha were arrested outside a nightclub in New York City for interfering with police after Chris Copeland of the Indiana Pacers was stabbed in the abdomen.

[29] During the month of July 2024, Antić was seen working as an assistant coach for the Phoenix Suns in the 2024 NBA Summer League out in Las Vegas.