Today, in addition to serving as a general aviation airport, several businesses, as well as a juvenile detention center/boot-camp and adult probation center are built upon former barracks and nearby areas.

The Perrin Air Force Base Historical Museum is located at the airport and Grayson County College uses several buildings.

After seeing the fighters take off from here as a young man, aviation expert Chesley Sullenberger (best known as the pilot of US Airways Flight 1549) became interested in flying.

[4][5] In late 2018, the proposed Christian airline Judah 1 moved to North Texas Regional, but was subsequently unsuccessful in its efforts to obtain an air operator's certificate and begin scheduled flights.

In the year ending April 30, 2007, the airport had 53,300 aircraft operations, an average of 146 per day: 98% general aviation, 2% military and <1% air taxi.