Perry-Spruill House, also known as Spruill House, is a historic home located at Plymouth, Washington County, North Carolina.

It was built between 1882 and 1884, and is a 1+1⁄2-story, three-bay, Gothic Revival style frame cottage.

It has a high hipped roof with intersecting cross gables ornamented with inverted fleur-de-lys sawnwork, a full-width front porch, pointed Gothic windows, and is sheathed in weatherboard.

[2] It was listed on the National Register of Historic Places in 1985.

This article about a property in Washington County, North Carolina on the National Register of Historic Places is a stub.