The building of the hospital was funded by public subscription and it opened on 1 October 1838.

[2] The current Perth Royal Infirmary was built on a site on Glasgow Road between 1912 and 1914.

Hospital Radio Perth are the winners of the UK Hospital Radio of the Year award four times 1996, 1997 1999 and 2007, making them one of the most successful stations in operation in the UK.

[9][10] Perth Royal Infirmary is roughly one mile from the city centre.

[11] In 2014, this service was replaced by an extension of the existing X7 Coastrider route.