Müller Argoviensis described the species' distinctive warts as small, irregularly hemispherical, and angular, sometimes only slightly raised from the surface, with multiple scattered ostioles that were hemispherically prominent and matched the thallus colour, except for dark brown spots in their centers.

[2] In his taxonomic assessment, Müller Argoviensis determined that P. texana was most closely related to P. meridionalis, but distinguished it by its differently coloured ostioles, which were the same color as the grayish-yellow warts except for occasionally yellowish tips and blackening centers, rather than being intensely sulfur-colored.

The type specimen was collected by Jacob Boll from tree bark near Dallas, Texas.

[3] Pertusaria texana can be confused with P. xanthodes, which shares similar chemical compounds but differs in having:[3] Another rare lookalike from Florida, P. epixanthoa, has depressed rather than raised ostioles, and variolaric rather than stictic acid.

[1] Pertusaria texana is a corticolous (bark-dwelling) species that grows on various trees including Acacia, Jatropha, and Quercus (oak).