Taught by his mother since 1923, he soon learned to play the piano and joined the family band La Rechiva del Son, directed by his uncles.
Los Trovadores del Tono was directed by drummer Aurelio Miró Jr., who shortly after moved to Havana, as did Peruchín and other members of the band.
[4] In Havana, Peruchín worked occasionally with Orquesta Casino de la Playa and Mariano Mercerón's orchestra.
In 1942 he joined Los Swing Boys, a big band directed by saxophonist Emilio Peñalver and featuring José "Chombo" Silva.
[8] Peruchín faded from the forefront of the Cuban jazz scene in the second half of the 1960s, giving way to up-and-coming figures such as Chucho Valdés.
Since 1972, he sometimes replaced Frank Emilio Flynn in his band Quinteto Instrumental de Música Moderna (also known as Los Amigos), featuring Cachaíto on bass, Guillermo Barreto on drums and Tata Güines on congas.
[13] Together with Lilí Martínez, Noro Morales and Jesús López, he is responsible for establishing the modern Cuban piano style.
[3] His son, Pedro Andrés Jústiz Márquez, "Peruchín Jr.", is a guitarist (and pianist too) who played with Orquesta Revé and Los Reyes '73, before directing his own band.