[5] After graduating from Great Neck North High School in 1979, Diamandis attended Hamilton College for his first year, then transferred to the Massachusetts Institute of Technology to study biology and physics.

[12] In 1987, during his third year of medical school, Diamandis cofounded International Space University with Todd Hawley, Walter Anderson, Christopher Mau and Robert Richards.

Diamandis cofounded Microsat Launch Systems, later renamed International MicroSpace Inc.,[17] in 1989 during his fourth year of medical school and served as the company's CEO.

[22] In 1994, Diamandis founded the XPRIZE Foundation after the failure of International MicroSpace, Inc[1] and reading Charles Lindbergh's The Spirit of St.

XPRIZE was created to fund and operate a $10 million incentive competition intended to inspire a new generation of private passenger-carrying spaceships.

SpaceShipOne was the world's first non-government piloted spacecraft[25] and hangs in the National Air and Space Museum adjacent to the Spirit of St. Louis aircraft.

[35] Its board of trustees includes Larry Page, Elon Musk, James Cameron, Dean Kamen, Ratan Tata, Ray Kurzweil, Jim Gianopulos, Naveen Jain, Arianna Huffington, Will Wright, and Craig Venter.

[37][38] In 2016, Julian Guthrie authored the book How to Make a Spaceship: A Band of Renegades, an Epic Race, and the Birth of Private Spaceflight, detailing the story behind the XPRIZE.

Corporation, which proposed to fly a private rover mission to land on the Moon as a mix of entertainment, Internet and space.

[51] In 2008, with the American author, inventor and futurist Ray Kurzweil, Diamandis cofounded Singularity University (SU), a Silicon Valley-based nonprofit offering education in futurology.

[53] SU is an interdisciplinary organization based on the NASA Ames campus in Silicon Valley and is supported by a number of corporate founders and partners including Autodesk, Cisco, Nokia, Kauffman Foundation and ePlanet Ventures.

[56] In April 2012, Diamandis cofounded Planetary Resources Inc., an organization dedicated to the identification, remote sensing and prospecting of near-Earth approaching asteroids, with Eric Anderson.

[63] In February 2018, Diamandis co-founded Celularity, a biotechnology company productizing allogeneic cells and tissues derived from the postpartum placenta, with Robert Hariri.

[72] The nonfiction work argues that advances in technology, entrepreneurship, and philanthropy have the potential to significantly raise global standards of living.

[76] In 2015, again with Steven Kotler, Diamandis coauthored Bold: How to Go Big, Create Wealth, and Impact the World,[77] which provides analysis and instruction for entrepreneurs interested in learning about exponential technologies, moon-shot thinking, and crowdsourcing.

The book, a New York Times bestseller, discusses various ways to boost energy, prevent disease, and extend vitality amidst health uncertainties.

[79] In January 2025, Peter Diamandis released Longevity Guidebook: How to Slow, Stop, and Reverse Aging — and NOT Die From Something Stupid.

[80] Diamandis hosts the MOONSHOTS Podcast, which has featured people such as Elon Musk, Cathie Wood, Michael Saylor, Eric Schmidt, and others about technological advancements.

In a follow-up article, Technology Review revealed that after COVID-19 had spread among attendees, an "informational webinar" was delivered by Matt Cook, a trained anesthesiologist from the San Francisco Bay Area who had started a medical practice using alternative therapies.

It is alleged that Cook tried to sell participants "fraudulent" treatments including inhaled amniotic fluid and ketamine lozenges, which a professor of law and medicine at Stanford University characterized as "quackery".