Born in Yerevan, Avetisyan started his career at Malatia football school that later was renamed as FC Banants.
On 29 July 2016, Avetisyan signed for Pyunik on a six-month loan deal,[5] and played almost all the matches in Starting line-up of the club in the first half of 2016–17 season.
[9][better source needed] Avetisyan made his Ararat-Armenia debut on 2 March 2019 in a 4–1 Premier League home win against Ararat Yerevan.
In the same season, Avetisyan won to the title of Armenian Premier League with Ararat-Armenia and became champion of Armenia for the first time.
[13] He made his debut for FC Tobol on 14 March 2020 in Kazakhstan Premier League Matchday 2 fixture against Zhetysu, as a 90th-minute substitute for Serikzhan Muzhikov.
[24] Avetisyan made his debut in Armenia national under-21 football team on 8 September 2015 in a home match against Romania.
[26] He made his debut for the senior squad on 26 March 2019 in a Euro 2020 qualifier against Finland, as a 74th-minute substitute for Edgar Babayan.