Pettibone is an unincorporated community in Milam County, Texas, United States.

Pettibone was a flag stop on the Gulf, Colorado and Santa Fe Railway, which built a track through the area in 1881.

[3] It is also on Texas State Highway 36 and Farm to Market Road 486.

Today, the community is served by the Cameron Independent School District.

This article about a location in Milam County, Texas is a stub.