It was designated a National Historic Landmark in 1973 as the home of Founding Father Peyton Randolph (1721–1775), the first and third President of the Continental Congress.

The Randolph House is located in near the center of Colonial Williamsburg, at the northeast corner of Nicholson and North England Streets.

The building interior retains original 18th century woodwork, and a marble fireplace mantel in its central section.

[4] During the American Civil War, the home was owned by the Peachy Family, and was used as a hospital for Union and Confederate troops wounded during the Battle of Williamsburg on May 5, 1862.

In 1970 the house was declared a National Historic Landmark, for its well-preserved early 18th-century architecture, and for its association with prominent Randolph family.