[3] In spite of its common name, it is more closely related to the lima bean (Phaseolus lunatus), and it holds potential as a crop wild relative due to its resistance to white mold (Sclerotinia sclerotiorum).

polystachios variety is listed as a special concern species and believed extirpated in Connecticut.

[6] Phaseolus polystachios has been found in a few Native American archaeological sites in Oklahoma and Arkansas, with some evidence of artificial selection for indehiscent (non-shattering) pods.

[7] Phaseolus polystachios exhibits hypogeal germination and is photoperiod sensitive, requiring day lengths greater than 10 hours to vine and flower.

[8][9] Phaseolus polystachios inhabits well-drained soils and slopes, generally woodlands and thickets, and may form colonies.