Phahonyothin Road, part of the AH2 Highway system, crosses the Phi Pan Nam Range area from north to south, between Tak and Chiang Rai.

[3] There are columnar basalt formations in Mon Hin Kong (Thai: ม่อนหินกอง) in an area in the mountains near Na Phun, Wang Chin District, Phrae Province.

[5] The Phi Pan Nam range system is often divided into two physiographic longitudinal sections: The highest point is the 1,694 metres (5,558 ft) high summit known as Doi Luang.

These mountains divide the Mekong from the Chao Phraya watershed and important rivers of Thailand have their source in the Phi Pan Nam area.

[27] Owing to the relative isolation of the area there was Communist insurgency in the mountainous forests of the Phi Pan Nam Range during the Cold War.

A memorial was erected on 1,118 m high Doi Phaya Phipak (ดอยพญาพิภักดิ์) to commemorate the victims of the battles between troops of the Royal Thai Armed Forces and the insurgents of the Communist Party of Thailand between the 1950s and the 1970s.

[29] A controversial dam was planned in the central area of the range on the Yom River in Kaeng Suea Ten in 1991 but this project was later abandoned in the face of popular opposition.

Protected sectors are typically surrounded by agricultural zones, often near roads and villages and thus with vast surfaces under the influence of the edge effect.

Some of the other species of trees found in the forests of the mountains are: Afzelia xylocarpa, Ailanthus triphysa, Anisoptera costata, Artocarpus lacucha, Berrya ammonilla, Betula alnoides, Cinnamomum iners, Dalbergia oliveri, Dillenia pentagyna, Dipterocarpus obtusifolius, Dipterocarpus alatus, Dipterocarpus turbinatus, Duabanga grandiflora, Garcinia indica, Hopea odorata, Irvingia malayana, Lagerstroemia loudonii, Lagerstroemia calyculata, Lagerstroemia tomentosa, Lithocarpus densiflorus, Mangifera caloneura, Michelia champaca, Michelia floribunda, Pterocarpus macrocarpus, Schleichera oleosa, Terminalia bellirica, Toona ciliata, Vitex pinnata and Xylia xylocarpa.

The endangered animal species sheltered by some of the fragmented, although relatively undisturbed Phi Pan Nam forests are the fishing cat, sun bear, Asiatic black bear, Chinese pangolin, Indochinese tiger, sambar deer, gaur, Bengal slow loris, Sunda pangolin, as well as the Asiatic softshell turtle and the big-headed turtle.

[42] The green peafowl, now rare in the wilderness and threatened by habitat destruction throughout Southeast Asia, breeds in the central mountains of the range from January to March.