Left penniless after the death of her husband Lars, Phyllis and her daughter Bess (Lisa Gerritsen) move in with Lars's mother, the scatterbrained Audrey Dexter (Jane Rose) and stepfather Judge Jonathan Dexter (Henry Jones).
Leo Heatherton (Richard Schaal, who was married to Valerie Harper, who played the title character in Rhoda) was a well-meaning but bumbling photographer at the studio.
Much of the first season's humor stemmed from Phyllis' attempts to fit into the job market, having lived for many years as the spoiled wife of a rich dermatologist.
Judith Lowry guest starred in an early episode ("Leaving Home") as Jonathan's mother, Sally Dexter.
She was so well received by viewers that by the end of the first year Lowry became a regular when Mother Dexter joined the household.
Aired on Monday nights between two popular shows – Rhoda and All in the Family – Phyllis instantly became a top ten hit.
She found romance with Mark Valenti (Craig Wasson), the nephew of Phyllis' boss, and they later married.
The complications resulting from the deaths of several cast members during the show's run, as well as the ill health of actress Jane Rose, are said to have been factors in the series' cancellation.
The same week, on Saturday, March 19, Leachman made her last appearance as Phyllis Lindstrom on the final episode of The Mary Tyler Moore Show.