Philomena Frances Ryan (28 February 1895 – 19 November 1983) was an Irish chemist and nationalist and the second wife of President of Ireland, Seán T. O'Kelly.

They were a nationalist family who "played an important role in revolutionary politics and helped shape the new Free State.

[3] Ryan and her sisters were involved in Cumann na mBan, two of whom were arrested and imprisoned after the Easter Rising.

Ryan reported for duty at the General Post Office, Dublin with her sisters, where they acted as messengers.

[4] The Ryan sisters also attempted to get the British army to stop firing on Red Cross locations.

[5] In the lead up to the events she and her sisters had acted as cover for the men meeting up, accompanying them to make it look like they were out with their girlfriends.

She wrote to her sister Min severing ties with herself and her husband Richard Mulcahy, a general in the Free State army, for the duration.

[8][12][14][13] In June 1946, Ryan organised a reunion event at Áras an Uachtaráin for members of Cumann na mBan,[17] Her husband served two terms as President of Ireland before retiring in 1959, at which point the couple moved to Roundwood, County Wicklow.