[1] Shell presents large and strong reaching sizes between 7–11 cm, with 4 or 5 lap varices, varices these are simple, nodular and obtuse, siphonal canal wide and curved.

The mouth has colors that can vary from yellow, orange and red and the inner lip is nodulated at the base.

[2][3][4][5] Studies in relation to the size of males and females suggests that females tend to have Phyllonotus margaritensis size larger than males and greater variation in shape.

[6] North Carolina to Florida and Caribbean Sea to Brazil.

[11] It has been collected in a bathymetric range from 0 to 200 m.[7] This muricid is an active predator of bivalves such as sand-dwelling clams.