[1] Pié Masumbuko was born on 29 September 1931 at Rukiga, Kiganda commune, Muramvya Province, Ruanda-Urundi.
He then received a secondary education and training as a medical assistant[2] at the Groupe Scolaire de Astrida.
[4] In 1963 he was arrested on the orders of Prime Minister André Muhirwa for plotting against the government, but was soon thereafter released upon the intervention of Mwami Mwambutsa IV.
[7] Masumbuko then served as acting Prime Minister of Burundi from then until he was succeeded by Joseph Bamina on 26 January.
[10] Following a coup in 1966, Masumbuko was appointed Minister of Foreign Affairs on 12 July by Mwami Ntare V.[11] The Mwami came increasingly into conflict with the government, and in September attempted to force Masumbuko to resign after a tract circulated accusing him of corruption.
[13] He was arrested by the regime on 6 July for allegedly contacting Congolese rebels to plot against the government[14] and eventually released on 28 November.